Star Trek: Supremacy is the successor of the original Star Trek: Birth of The Federation. The game can be played with up to 6 major races (Earth Federation, Kardasiani, Klingon, Ferengi and even Dominion) in a large star map.
We could say that this is a game resembling Master of Orion because the game is really that type. The player will be able to explore the vast galaxy, colonizing new systems to develop science, to spy, to manipulate diplomacy and to fight and conquer.
Download, unzip and run. The game has an automatic update and during the first start it will probably ask to update.
The game requires that you have installed .NET Framework 3.5
Game intro (Federation):